Correction to: A Novel Somatic Variant in HEY2 Unveils an Alternative Splicing Isoform Linked to Ventricular Septal Defect

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Correction: A Novel CDX2 Isoform Regulates Alternative Splicing

Citation: The PLOS ONE Staff (2014) Correction: A Novel CDX2 Isoform Regulates Alternative Splicing. PLoS ONE 9(10): e112164. doi:10.1371/journal.pone.0112164 Published October 23, 2014 Copyright: 2014 The PLOS ONE Staff. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any m...

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A Novel CDX2 Isoform Regulates Alternative Splicing

Gene expression is a dynamic and coordinated process coupling transcription with pre-mRNA processing. This regulation enables tissue-specific transcription factors to induce expression of specific transcripts that are subsequently amplified by alternative splicing allowing for increased proteome complexity and functional diversity. The intestine-specific transcription factor CDX2 regulates deve...

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Ministernotomy for correction of ventricular septal defect.

BACKGROUND The development of minimally invasive surgery in the adult has created motivation for similar approaches in the congenital heart domain. Over the past 20 years, this type of surgery has been advocated in an effort to reduce costs related to hospital stay, and to improve the cosmetic results. We report our experience with ventricular septal defect repair utilizing a ministernotomy inc...

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A novel NKX2-5 mutation in familial ventricular septal defect.

Ventricular septal defect (VSD) is the most common cardiovascular malformation and an important contributor to the substantial morbidity and mortality in infancy. Growing evidence suggests that genetic defects play important roles in the pathogenesis of congenital VSD. However, VSD is of great genetic heterogeneity and the genetic basis for VSD in the majority of the patients remains largely un...

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Ventricular septal defect: a review.

Henri Roger, in 1879, was the first to accurately describe the clinical manifestations of ventricular septal defect, and the term “maladie de Roger” is often used in connection with these malformations. The lesion and the problems associated with it have attracted a great deal of attention in recent years, particularly with the advent of open heart surgery and a means for affecting a cure. Embr...

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ژورنال

عنوان ژورنال: Pediatric Cardiology

سال: 2019

ISSN: 0172-0643,1432-1971

DOI: 10.1007/s00246-019-02120-4